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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PTEN
All Species:
9.09
Human Site:
Y336
Identified Species:
25
UniProt:
P60484
Number Species:
8
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P60484
NP_000305.3
403
47166
Y336
N
K
D
K
A
N
R
Y
F
S
P
N
F
K
V
Chimpanzee
Pan troglodytes
XP_521544
462
52650
V393
D
K
M
F
H
F
W
V
N
T
F
F
I
P
G
Rhesus Macaque
Macaca mulatta
XP_001102446
270
31559
F204
K
D
K
A
N
R
Y
F
S
P
N
F
K
V
K
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
O08586
403
47134
Y336
N
K
D
K
A
N
R
Y
F
S
P
N
F
K
V
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506371
391
45262
Y324
N
K
D
K
A
N
R
Y
F
S
P
N
F
K
V
Chicken
Gallus gallus
Frog
Xenopus laevis
Q9PUT6
402
46859
L335
N
K
D
K
A
N
R
L
F
S
P
N
F
K
V
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_599147
509
58413
K422
T
S
T
A
C
K
R
K
Q
P
N
S
K
T
L
Honey Bee
Apis mellifera
NP_001155985
501
56758
V363
H
K
D
K
H
H
K
V
Y
S
A
D
F
K
V
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001177499
393
45424
D309
N
M
E
A
L
D
A
D
C
T
V
L
R
L
Q
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
74.4
67
N.A.
N.A.
99.7
N.A.
N.A.
77.4
N.A.
88.5
N.A.
N.A.
34.1
40.7
N.A.
54
Protein Similarity:
100
74.4
67
N.A.
N.A.
100
N.A.
N.A.
83.6
N.A.
93.8
N.A.
N.A.
50
56.8
N.A.
68.2
P-Site Identity:
100
6.6
0
N.A.
N.A.
100
N.A.
N.A.
100
N.A.
93.3
N.A.
N.A.
6.6
46.6
N.A.
6.6
P-Site Similarity:
100
20
6.6
N.A.
N.A.
100
N.A.
N.A.
100
N.A.
93.3
N.A.
N.A.
20
80
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
34
45
0
12
0
0
0
12
0
0
0
0
% A
% Cys:
0
0
0
0
12
0
0
0
12
0
0
0
0
0
0
% C
% Asp:
12
12
56
0
0
12
0
12
0
0
0
12
0
0
0
% D
% Glu:
0
0
12
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
12
0
12
0
12
45
0
12
23
56
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
12
% G
% His:
12
0
0
0
23
12
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
12
0
0
% I
% Lys:
12
67
12
56
0
12
12
12
0
0
0
0
23
56
12
% K
% Leu:
0
0
0
0
12
0
0
12
0
0
0
12
0
12
12
% L
% Met:
0
12
12
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
56
0
0
0
12
45
0
0
12
0
23
45
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
23
45
0
0
12
0
% P
% Gln:
0
0
0
0
0
0
0
0
12
0
0
0
0
0
12
% Q
% Arg:
0
0
0
0
0
12
56
0
0
0
0
0
12
0
0
% R
% Ser:
0
12
0
0
0
0
0
0
12
56
0
12
0
0
0
% S
% Thr:
12
0
12
0
0
0
0
0
0
23
0
0
0
12
0
% T
% Val:
0
0
0
0
0
0
0
23
0
0
12
0
0
12
56
% V
% Trp:
0
0
0
0
0
0
12
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
12
34
12
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _